Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02666
Pert ID: BRD-K14618467
Compound Name: IKK-16
Targets: IKBKB
MoA: IKK inhibitor
SMILES: O=C(N1CCC(CC1)N1CCCC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
473 BRD-K14618467 BJAB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
519 BRD-K14618467 HBL1 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
584 BRD-K14618467 K562 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
611 BRD-K14618467 KMS34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
656 BRD-K14618467 MINO 2.5 uM 24 h -0.28 -1.16 0.48 0.0 0.0 0.0
703 BRD-K14618467 NALM6 2.5 uM 24 h 0.21 0.87 0.01 0.36 1.27 1.34
778 BRD-K14618467 OCILY19 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
798 BRD-K14618467 OCILY3 10 uM 24 h -0.27 -1.12 0.38 0.0 0.0 0.0
844 BRD-K14618467 SKMEL5 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
893 BRD-K14618467 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
949 BRD-K14618467 TMD8 2.5 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
1742 BRD-K14618467 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2086 BRD-K14618467 HCC515 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
2276 BRD-K14618467 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2615 BRD-K14618467 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
41734 BRD-K14618467 A375 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.47
42067 BRD-K14618467 A549 10 uM 6 h 0.2 0.83 0.0 -0.3 -1.02 0.6
42309 BRD-K14618467 ASC 10 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
42640 BRD-K14618467 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42944 BRD-K14618467 HT29 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.64
43298 BRD-K14618467 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44077 BRD-K14618467 SKB 10 uM 24 h 0.27 1.13 0.29 0.0 0.0 0.0
90817 BRD-K14618467 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
100118 BRD-K14618467 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).