CMap Candidate Details
Structure:
| CMap ID: | C00270 |
| Pert ID: | BRD-K21728777 |
| Compound Name: | AMG900 |
| Targets: | AURKA|AURKB|AURKC |
| MoA: | Aurora kinase inhibitor |
| SMILES: | Cc1csc(c1)-c1nnc(Nc2ccc(Oc3ncccc3-c3ccnc(N)n3)cc2)c2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96964 | BRD-K21728777 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 97045 | BRD-K21728777 | PC3 | 10 uM | 24 h | -0.23 | -0.96 | 0.1 | -0.5 | -1.7 | 15.65 |