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CMap Candidate Details

Structure:
CMap ID: C02701
Pert ID: BRD-K90948141
Compound Name: indiplon
Targets: GABRA1
MoA: benzodiazepine receptor agonist
SMILES: CN(C(C)=O)c1cccc(c1)-c1ccnc2c(cnn12)C(=O)c1cccs1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96599 BRD-K90948141 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127783 BRD-K90948141 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
127863 BRD-K90948141 HEK293 3.33 uM 24 h 0.22 0.94 0.05 0.0 0.0 0.0
127937 BRD-K90948141 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.36
127990 BRD-K90948141 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
128049 BRD-K90948141 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128076 BRD-K90948141 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
135527 BRD-K90948141 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135564 BRD-K90948141 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.06
135611 BRD-K90948141 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135655 BRD-K90948141 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135694 BRD-K90948141 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).