CMap Candidate Details
Structure:
CMap ID: | C02703 |
Pert ID: | BRD-K19136521 |
Compound Name: | indirubin-3-monoxime |
Targets: | CDK1|CDK2|CDK5|CDK5R1|GSK3B |
MoA: | CDK inhibitor; glycogen synthase kinase inhibitor |
SMILES: | O\N=C1c2ccccc2NC/1=C1\C(=O)Nc2ccccc12 |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
5306 | BRD-K19136521 | HA1E | 10 uM | 24 h | 0.32 | 1.34 | 0.89 | 0.0 | 0.0 | 0.0 |
5590 | BRD-K19136521 | HCC515 | 10 uM | 24 h | -0.17 | -0.72 | 0.0 | -0.3 | -1.01 | 0.56 |
6264 | BRD-K19136521 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.97 | 0.35 |
6527 | BRD-K19136521 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
37130 | BRD-K19136521 | A375 | 10 uM | 6 h | -0.29 | -1.2 | 0.57 | 0.0 | 0.0 | 0.0 |
37273 | BRD-K19136521 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.4 |
37609 | BRD-K19136521 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
37878 | BRD-K19136521 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
38061 | BRD-K19136521 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
38187 | BRD-K19136521 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
38439 | BRD-K19136521 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
38922 | BRD-K19136521 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |