CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02712
Pert ID:	BRD-A44090213
Compound Name:	indoprofen
Targets:	CXCR1\|CXCR2\|PTGS1\|PTGS2
MoA:	cyclooxygenase inhibitor; prostanoid receptor antagonist
SMILES:	CC(C(O)=O)c1ccc(cc1)N1Cc2ccccc2C1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
8757	BRD-A44090213	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
123250	BRD-A44090213	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123282	BRD-A44090213	HA1E	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123326	BRD-A44090213	HELA	10 uM	24 h	-0.32	-1.31	0.82	0.0	0.0	0.0
123439	BRD-A44090213	PC3	0.04 uM	24 h	0.0	0.0	0.0	0.24	0.85	0.14
131565	BRD-A44090213	A549	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131644	BRD-A44090213	HEK293	2.22 uM	24 h	0.21	0.87	0.01	0.0	0.0	0.0
131694	BRD-A44090213	HT29	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131747	BRD-A44090213	HUVEC	0.74 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.66
131802	BRD-A44090213	JURKAT	0.03 uM	24 h	0.0	0.0	0.0	-0.28	-0.95	0.42
131835	BRD-A44090213	MCF10A	2.22 uM	24 h	0.0	0.0	0.0	-0.3	-1.01	0.57
131875	BRD-A44090213	MCF??7.00	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131907	BRD-A44090213	MDAMB231	0.08 uM	24 h	-0.3	-1.23	0.64	0.0	0.0	0.0
131942	BRD-A44090213	THP1	0.25 uM	24 h	0.0	0.0	0.0	0.27	0.96	0.33
131962	BRD-A44090213	YAPC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary