CMap Candidate Details
Structure:
| CMap ID: | C02714 |
| Pert ID: | BRD-K93255255 |
| Compound Name: | indoximod |
| Targets: | IDO1 |
| MoA: | indoleamine 2,3-dioxygenase inhibitor |
| SMILES: | Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 128129 | BRD-K93255255 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128181 | BRD-K93255255 | HT29 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.91 | 0.3 |
| 128206 | BRD-K93255255 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128285 | BRD-K93255255 | MDAMB231 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.88 | 0.24 |
| 128345 | BRD-K93255255 | THP1 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.02 | 0.47 |
| 135753 | BRD-K93255255 | A375 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135795 | BRD-K93255255 | HA1E | 0.25 uM | 24 h | -0.29 | -1.19 | 0.53 | 0.0 | 0.0 | 0.0 |
| 135840 | BRD-K93255255 | HEK293 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135880 | BRD-K93255255 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.47 |
| 135969 | BRD-K93255255 | JURKAT | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136020 | BRD-K93255255 | MCF??7.00 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -0.99 | 0.51 |
| 136048 | BRD-K93255255 | PC3 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 136115 | BRD-K93255255 | YAPC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |