CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02744
Pert ID:	BRD-K70751730
Compound Name:	IOX1
Targets:	EGLN1\|KDM3A\|KDM4C\|KDM6B
MoA:	histone demethylase inhibitor
SMILES:	OC(=O)c1ccc(O)c2ncccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
21902	BRD-K70751730	A375	10 uM	6 h	0.0	0.0	0.0	-0.37	-1.24	1.35
22551	BRD-K70751730	HA1E	10 uM	6 h	0.28	1.16	0.35	0.0	0.0	0.0
23132	BRD-K70751730	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
23422	BRD-K70751730	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
23625	BRD-K70751730	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
23892	BRD-K70751730	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
24200	BRD-K70751730	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
115164	BRD-K70751730	U2OS	20 uM	6 h	0.0	0.0	0.0	-0.22	-0.75	0.06

Summary