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CMap Candidate Details

Structure:
CMap ID: C02745
Pert ID: BRD-K98251413
Compound Name: IOX2
Targets: EGLN1|KDM2A|KDM5C
MoA: hypoxia inducible factor inhibitor
SMILES: OC(=O)CNC(=O)c1c(O)c2ccccc2n(Cc2ccccc2)c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
93609 BRD-K98251413 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93643 BRD-K98251413 ASC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93699 BRD-K98251413 CD34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93748 BRD-K98251413 HA1E 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93784 BRD-K98251413 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93827 BRD-K98251413 HEK293 10 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
93875 BRD-K98251413 HELA 10 uM 24 h -0.21 -0.87 0.02 0.25 0.87 0.17
93916 BRD-K98251413 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93983 BRD-K98251413 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94012 BRD-K98251413 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94054 BRD-K98251413 MCF??7.00 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94091 BRD-K98251413 NEU 3.33 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
94153 BRD-K98251413 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94189 BRD-K98251413 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94224 BRD-K98251413 SHSY5Y 10 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
94275 BRD-K98251413 SKL 10 uM 24 h -0.25 -1.04 0.21 0.32 1.15 0.88
94326 BRD-K98251413 THP1 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
94370 BRD-K98251413 YAPC 10 uM 24 h -0.25 -1.06 0.25 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).