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CMap Candidate Details

Structure:
CMap ID: C02772
Pert ID: BRD-A07704283
Compound Name: isofloxythepin
Targets:
MoA: dopamine receptor antagonist
SMILES: CC(C)c1ccc2Sc3cc(F)ccc3CC(N3CCN(CCO)CC3)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122589 BRD-A07704283 A549 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
122611 BRD-A07704283 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122647 BRD-A07704283 HEK293 1.11 uM 24 h -0.21 -0.89 0.04 0.28 0.99 0.41
122690 BRD-A07704283 HT29 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
122742 BRD-A07704283 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122804 BRD-A07704283 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130875 BRD-A07704283 A375 0.25 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.98
130982 BRD-A07704283 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131064 BRD-A07704283 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
131097 BRD-A07704283 MCF??7.00 2.22 uM 24 h 0.24 1.01 0.11 0.0 0.0 0.0
131132 BRD-A07704283 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
131195 BRD-A07704283 YAPC 0.08 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).