Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02778
Pert ID: BRD-K33583600
Compound Name: isoliquiritigenin
Targets: GABBR1
MoA: guanylate cyclase activator
SMILES: Oc1ccc(cc1)\C=C\C(=O)c1ccc(O)cc1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8936 BRD-K33583600 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9199 BRD-K33583600 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9411 BRD-K33583600 AGS 10 uM 6 h 0.0 0.0 0.0 0.37 1.3 1.49
9718 BRD-K33583600 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9960 BRD-K33583600 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10330 BRD-K33583600 HCC515 10 uM 6 h 0.21 0.86 0.01 0.0 0.0 0.0
10506 BRD-K33583600 HCT116 10 uM 6 h 0.0 0.0 0.0 0.35 1.23 1.2
10777 BRD-K33583600 HEPG2 10 uM 6 h -0.27 -1.11 0.36 0.3 1.05 0.57
11100 BRD-K33583600 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11210 BRD-K33583600 MCF??7.00 10 uM 24 h -0.28 -1.16 0.46 0.32 1.13 0.82
11473 BRD-K33583600 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11753 BRD-K33583600 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12037 BRD-K33583600 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12532 BRD-K33583600 PC3 10 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
12780 BRD-K33583600 SW480 10 uM 6 h -0.28 -1.17 0.48 0.0 0.0 0.0
13058 BRD-K33583600 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13261 BRD-K33583600 U937 10 uM 6 h -0.24 -0.98 0.12 0.34 1.22 1.15
13469 BRD-K33583600 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99858 BRD-K33583600 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).