Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02795
Pert ID: BRD-A75552914
Compound Name: isoxicam
Targets: PTGS1|PTGS2
MoA: cyclooxygenase inhibitor
SMILES: CN1C(C(=O)Nc2cc(C)on2)C(=O)c2ccccc2S1(=O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5280 BRD-A75552914 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5550 BRD-A75552914 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5859 BRD-A75552914 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5993 BRD-A75552914 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6249 BRD-A75552914 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6323 BRD-A75552914 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37103 BRD-A75552914 A375 10 uM 6 h 0.27 1.11 0.25 0.0 0.0 0.0
37356 BRD-A75552914 A549 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.73 0.04
37551 BRD-A75552914 ASC 10 uM 24 h -0.23 -0.98 0.12 -0.31 -1.03 0.64
38245 BRD-A75552914 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38393 BRD-A75552914 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38664 BRD-A75552914 PHH 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
38888 BRD-A75552914 SKB 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).