CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02798
Pert ID:	BRD-A90799790
Compound Name:	isradipine
Targets:	CACNA1C\|CACNA1D\|CACNA1F\|CACNA1H\|CACNA1S\|CACNA2D1\|CACNA2D2\|CACNB2
MoA:	calcium channel blocker
SMILES:	COC(=O)C1=C(C)NC(C)=C(C1c1cccc2nonc12)C(=O)OC(C)C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1469	BRD-A90799790	NPC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7605	BRD-A90799790	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
8633	BRD-A90799790	VCAP	10 uM	24 h	-0.23	-0.96	0.1	0.29	1.02	0.48
127342	BRD-A90799790	A375	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.16	1.1
127384	BRD-A90799790	A549	1.11 uM	24 h	-0.26	-1.08	0.29	0.0	0.0	0.0
127415	BRD-A90799790	HA1E	3.33 uM	24 h	0.0	0.0	0.0	0.2	0.7	0.01
127458	BRD-A90799790	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127503	BRD-A90799790	JURKAT	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127597	BRD-A90799790	PC3	10 uM	24 h	0.0	0.0	0.0	0.15	0.52	0.0
127639	BRD-A90799790	THP1	0.37 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.38
127673	BRD-A90799790	YAPC	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135392	BRD-A90799790	HT29	0.03 uM	24 h	-0.3	-1.24	0.64	0.0	0.0	0.0
135432	BRD-A90799790	MCF10A	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135465	BRD-A90799790	MCF??7.00	2.22 uM	24 h	-0.26	-1.1	0.34	0.0	0.0	0.0

Summary