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CMap Candidate Details

Structure:
CMap ID: C02802
Pert ID: BRD-K53903639
Compound Name: ISX-9
Targets: NEUROD1
MoA: neural stem cell inducer
SMILES: O=C(NC1CC1)c1cc(on1)-c1cccs1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9026 BRD-K53903639 A375 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9103 BRD-K53903639 A549 80 uM 24 h -0.31 -1.29 0.79 0.0 0.0 0.0
9443 BRD-K53903639 AGS 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9749 BRD-K53903639 H1299 80 uM 6 h -0.31 -1.29 0.79 0.0 0.0 0.0
9892 BRD-K53903639 HA1E 80 uM 24 h -0.17 -0.7 0.0 0.0 0.0 0.0
10138 BRD-K53903639 HCC515 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10535 BRD-K53903639 HCT116 80 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.33
10801 BRD-K53903639 HEPG2 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11065 BRD-K53903639 HT29 80 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.78
11149 BRD-K53903639 MCF??7.00 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11510 BRD-K53903639 NCIH2073 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11781 BRD-K53903639 NCIH508 80 uM 6 h 0.0 0.0 0.0 0.21 0.73 0.03
12070 BRD-K53903639 NCIH596 80 uM 6 h 0.18 0.74 0.0 0.0 0.0 0.0
12610 BRD-K53903639 PC3 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12811 BRD-K53903639 SW480 80 uM 6 h 0.0 0.0 0.0 0.32 1.13 0.84
12964 BRD-K53903639 THP1 80 uM 6 h 0.18 0.74 0.0 0.0 0.0 0.0
13296 BRD-K53903639 U937 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13482 BRD-K53903639 VCAP 80 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).