CMap Candidate Details
Structure:
| CMap ID: | C02808 |
| Pert ID: | BRD-A23067620 |
| Compound Name: | itraconazole |
| Targets: | CYP51A1 |
| MoA: | cytochrome P450 inhibitor |
| SMILES: | CCC(C)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@H]3CO[C@@](Cn4cncn4)(O3)c3ccc(Cl)cc3Cl)cc2)c1=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121377 | BRD-A23067620 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.45 |
| 121392 | BRD-A23067620 | HA1E | 10 uM | 24 h | -0.27 | -1.14 | 0.43 | -0.29 | -0.97 | 0.46 |
| 121424 | BRD-A23067620 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121489 | BRD-A23067620 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121538 | BRD-A23067620 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129505 | BRD-A23067620 | HT29 | 2.22 uM | 24 h | -0.23 | -0.97 | 0.11 | 0.0 | 0.0 | 0.0 |
| 129537 | BRD-A23067620 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.05 | 0.69 |