CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02848
Pert ID:	BRD-K63150726
Compound Name:	JTE-907
Targets:	CNR2
MoA:	cannabinoid receptor inverse agonist
SMILES:	CCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc4OCOc4c3)c(=O)[nH]c12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1595	BRD-K63150726	HA1E	10 uM	24 h	-0.24	-1.02	0.18	0.0	0.0	0.0
1936	BRD-K63150726	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
2506	BRD-K63150726	VCAP	10 uM	24 h	0.16	0.66	0.0	0.0	0.0	0.0
42424	BRD-K63150726	ASC	10 uM	24 h	0.0	0.0	0.0	0.25	0.89	0.21
42740	BRD-K63150726	HEPG2	10 uM	6 h	-0.25	-1.04	0.22	0.0	0.0	0.0
43339	BRD-K63150726	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43605	BRD-K63150726	NPC	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.47
43907	BRD-K63150726	PHH	10 uM	24 h	-0.2	-0.81	0.0	-0.25	-0.85	0.2
44164	BRD-K63150726	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99316	BRD-K63150726	U2OS	10 uM	6 h	-0.21	-0.87	0.02	0.25	0.88	0.18
124963	BRD-K63150726	A549	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.9	0.28
125053	BRD-K63150726	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125074	BRD-K63150726	MCF10A	3.33 uM	24 h	0.23	0.98	0.08	0.28	1.01	0.44
125109	BRD-K63150726	MDAMB231	10 uM	24 h	0.0	0.0	0.0	0.2	0.7	0.02
125131	BRD-K63150726	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125159	BRD-K63150726	THP1	10 uM	24 h	0.0	0.0	0.0	-0.37	-1.26	1.36
132977	BRD-K63150726	A375	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133045	BRD-K63150726	HEK293	0.03 uM	24 h	0.0	0.0	0.0	0.3	1.05	0.56
133090	BRD-K63150726	HELA	0.74 uM	24 h	0.23	0.97	0.08	-0.32	-1.06	0.74
133152	BRD-K63150726	JURKAT	0.74 uM	24 h	0.0	0.0	0.0	-0.43	-1.43	15.35
133313	BRD-K63150726	YAPC	0.74 uM	24 h	0.0	0.0	0.0	0.26	0.93	0.27

Summary