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CMap Candidate Details

Structure:
CMap ID: C02864
Pert ID: BRD-A07815743
Compound Name: kakonein
Targets:
MoA: GABA receptor antagonist; serotonin receptor antagonist
SMILES: OCC1OC(C(O)C(O)C1O)c1c(O)ccc2c1occ(-c1ccc(O)cc1)c2=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122588 BRD-A07815743 A549 0.04 uM 24 h -0.18 -0.75 0.0 0.0 0.0 0.0
122645 BRD-A07815743 HEK293 0.125 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
122740 BRD-A07815743 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122778 BRD-A07815743 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130874 BRD-A07815743 A375 0.03 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
130923 BRD-A07815743 HA1E 0.74 uM 24 h -0.25 -1.04 0.22 -0.27 -0.9 0.29
130980 BRD-A07815743 HELA 0.01 uM 24 h 0.28 1.16 0.35 0.36 1.27 1.34
131008 BRD-A07815743 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
131062 BRD-A07815743 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.22 0.76 0.05
131095 BRD-A07815743 MCF??7.00 0.03 uM 24 h -0.18 -0.75 0.0 0.22 0.77 0.06
131160 BRD-A07815743 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131194 BRD-A07815743 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).