CMap Candidate Details
Structure:
| CMap ID: | C02869 |
| Pert ID: | BRD-A00376169 |
| Compound Name: | KBG |
| Targets: | MME |
| MoA: | neprilysin inhibitor |
| SMILES: | OC1O[C@@H]2COC(O[C@H]2[C@H](O)[C@H]1O)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122876 | BRD-A00376169 | HEK293 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122960 | BRD-A00376169 | HT29 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123001 | BRD-A00376169 | JURKAT | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123052 | BRD-A00376169 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.2 | 1.16 |
| 123090 | BRD-A00376169 | MDAMB231 | 0.37 uM | 24 h | 0.28 | 1.19 | 0.41 | -0.22 | -0.73 | 0.04 |
| 123142 | BRD-A00376169 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123162 | BRD-A00376169 | THP1 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131199 | BRD-A00376169 | A375 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131228 | BRD-A00376169 | A549 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.78 | 0.09 |
| 131269 | BRD-A00376169 | HA1E | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.05 | 0.68 |
| 131297 | BRD-A00376169 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.01 | 0.44 |
| 131338 | BRD-A00376169 | HUVEC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131423 | BRD-A00376169 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131481 | BRD-A00376169 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |