CMap Candidate Details
Structure:
| CMap ID: | C02870 |
| Pert ID: | BRD-K71164191 |
| Compound Name: | KD-023 |
| Targets: | ACACA|ACACB |
| MoA: | ACAT inhibitor |
| SMILES: | CCCCCCCCCCCCCCOc1ccc(o1)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96766 | BRD-K71164191 | PC3 | 10 uM | 24 h | 0.28 | 1.17 | 0.36 | 0.0 | 0.0 | 0.0 |
| 126635 | BRD-K71164191 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.79 |
| 126655 | BRD-K71164191 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126748 | BRD-K71164191 | HT29 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.18 | 1.14 |
| 126851 | BRD-K71164191 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126895 | BRD-K71164191 | MDAMB231 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.24 | 1.27 |
| 126963 | BRD-K71164191 | THP1 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127001 | BRD-K71164191 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 134737 | BRD-K71164191 | HA1E | 2.22 uM | 24 h | -0.22 | -0.9 | 0.05 | 0.0 | 0.0 | 0.0 |
| 134772 | BRD-K71164191 | HEK293 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 134801 | BRD-K71164191 | HELA | 0.08 uM | 24 h | 0.35 | 1.45 | 1.12 | 0.0 | 0.0 | 0.0 |
| 134877 | BRD-K71164191 | HUVEC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 134903 | BRD-K71164191 | JURKAT | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.86 | 0.15 |
| 134932 | BRD-K71164191 | MCF10A | 0.74 uM | 24 h | -0.22 | -0.92 | 0.06 | -0.34 | -1.15 | 1.07 |