CMap Candidate Details
Structure:
| CMap ID: | C02874 |
| Pert ID: | BRD-K29113274 |
| Compound Name: | ketoconazole |
| Targets: | AR|CYP19A1|CYP21A2|KCNA10 |
| MoA: | sterol demethylase inhibitor |
| SMILES: | CC(=O)N1CCN(CC1)c1ccc(OC[C@H]2CO[C@@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24662 | BRD-K29113274 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24889 | BRD-K29113274 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.96 | 0.33 |
| 25015 | BRD-K29113274 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.99 | 0.4 |
| 25347 | BRD-K29113274 | VCAP | 10 uM | 24 h | -0.27 | -1.13 | 0.41 | 0.0 | 0.0 | 0.0 |
| 91141 | BRD-K29113274 | HUH7 | 6.66 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96575 | BRD-K29113274 | A375 | 1.11 uM | 24 h | -0.21 | -0.86 | 0.02 | 0.0 | 0.0 | 0.0 |
| 96646 | BRD-K29113274 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99807 | BRD-K29113274 | U2OS | 4 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |