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CMap Candidate Details

Structure:
CMap ID: C02894
Pert ID: BRD-K93480852
Compound Name: KN-93
Targets: CAMK2A
MoA: calcium/calmodulin dependent protein kinase inhibitor
SMILES: COc1ccc(cc1)S(=O)(=O)N(CCO)c1ccccc1CN(C)C\C=C\c1ccc(Cl)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2946 BRD-K93480852 HA1E 10 uM 24 h 0.0 0.0 0.0 0.39 1.36 1.78
3294 BRD-K93480852 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3568 BRD-K93480852 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3899 BRD-K93480852 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39840 BRD-K93480852 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40129 BRD-K93480852 HEPG2 10 uM 6 h -0.39 -1.63 15.35 0.0 0.0 0.0
40387 BRD-K93480852 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40540 BRD-K93480852 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.39
40936 BRD-K93480852 NEU 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
41601 BRD-K93480852 SKB 10 uM 24 h 0.26 1.09 0.22 0.38 1.35 1.72
95773 BRD-K93480852 A375 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95817 BRD-K93480852 NPC 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95842 BRD-K93480852 A549 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95944 BRD-K93480852 YAPC 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).