CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02911
Pert ID:	BRD-K29968218
Compound Name:	KX2-391
Targets:	SRC
MoA:	src inhibitor; tubulin polymerization inhibitor
SMILES:	O=C(Cc1ccc(cn1)-c1ccc(OCCN2CCOCC2)cc1)NCc1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
122048	BRD-K29968218	HUVEC	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122106	BRD-K29968218	MCF??7.00	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122165	BRD-K29968218	PC3	1.11 uM	24 h	-0.23	-0.96	0.1	-0.35	-1.18	1.14
122192	BRD-K29968218	THP1	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130184	BRD-K29968218	A375	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130203	BRD-K29968218	A549	0.74 uM	24 h	-0.22	-0.91	0.05	0.0	0.0	0.0
130227	BRD-K29968218	HA1E	2.22 uM	24 h	-0.21	-0.88	0.03	-0.32	-1.06	0.74
130257	BRD-K29968218	HEK293	2.22 uM	24 h	0.0	0.0	0.0	-0.35	-1.17	1.13
130289	BRD-K29968218	HELA	0.25 uM	24 h	-0.23	-0.96	0.09	-0.38	-1.28	1.45
130317	BRD-K29968218	HT29	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130349	BRD-K29968218	JURKAT	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130398	BRD-K29968218	MCF10A	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130449	BRD-K29968218	MDAMB231	2.22 uM	24 h	0.0	0.0	0.0	-0.23	-0.76	0.07
130520	BRD-K29968218	YAPC	0.01 uM	24 h	-0.17	-0.71	0.0	0.23	0.82	0.1

Summary