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CMap Candidate Details

Structure:
CMap ID: C02981
Pert ID: BRD-A72711497
Compound Name: lasalocid
Targets:
MoA: bacterial permeability inducer
SMILES: CC[C@H](C1OC(CC)(C[C@@H]1C)C1CC[C@](O)(CC)[C@H](C)O1)C(=O)C(C)[C@@H](O)[C@H](C)CCc1ccc(C)c(O)c1C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6853 BRD-A72711497 A375 10 uM 6 h -0.31 -1.29 0.78 0.2 0.72 0.03
7587 BRD-A72711497 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8062 BRD-A72711497 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8617 BRD-A72711497 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100313 BRD-A72711497 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
126680 BRD-A72711497 HA1E 1.11 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
126701 BRD-A72711497 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126730 BRD-A72711497 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126754 BRD-A72711497 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126819 BRD-A72711497 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126975 BRD-A72711497 THP1 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
134712 BRD-A72711497 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134889 BRD-A72711497 HUVEC 2.22 uM 24 h 0.24 1.02 0.13 0.0 0.0 0.0
134911 BRD-A72711497 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.45 1.6 2.37
134947 BRD-A72711497 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134975 BRD-A72711497 PC3 2.22 uM 24 h 0.31 1.28 0.6 0.28 0.98 0.38
135005 BRD-A72711497 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).