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CMap Candidate Details

Structure:
CMap ID: C03023
Pert ID: BRD-K24526313
Compound Name: levcromakalim
Targets: KCNJ5
MoA: potassium channel activator
SMILES: CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1CCCC1=O)C#N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1748 BRD-K24526313 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1905 BRD-K24526313 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2385 BRD-K24526313 PC3 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.27
2788 BRD-K24526313 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42079 BRD-K24526313 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42333 BRD-K24526313 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42658 BRD-K24526313 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42963 BRD-K24526313 HT29 10 uM 6 h 0.0 0.0 0.0 0.2 0.71 0.02
43175 BRD-K24526313 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43525 BRD-K24526313 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43823 BRD-K24526313 PHH 10 uM 24 h -0.25 -1.02 0.18 -0.31 -1.05 0.71
99770 BRD-K24526313 U2OS 10 uM 6 h -0.25 -1.02 0.18 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).