CMap Candidate Details
Structure:
| CMap ID: | C03085 |
| Pert ID: | BRD-K04497194 |
| Compound Name: | lithocholic-acid |
| Targets: | GPBAR1|NR1H4|NR1I2|VDR |
| MoA: | FXR antagonist; vitamin D receptor agonist |
| SMILES: | C[C@H](CCC(O)=O)[C@@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 51583 | BRD-K04497194 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51914 | BRD-K04497194 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.92 | 0.25 |