CMap Candidate Details
Structure:
| CMap ID: | C03104 |
| Pert ID: | BRD-K51768138 |
| Compound Name: | lomustine |
| Targets: | STMN4 |
| MoA: | DNA synthesis inhibitor |
| SMILES: | [O-][N+]N(CCCl)C(=O)NC1CCCCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91206 | BRD-K51768138 | HUH7 | 15 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117330 | BRD-K51768138 | A375 | 0.125 uM | 24 h | 0.24 | 0.99 | 0.09 | 0.0 | 0.0 | 0.0 |
| 117372 | BRD-K51768138 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117410 | BRD-K51768138 | HA1E | 1.11 uM | 24 h | -0.2 | -0.82 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117453 | BRD-K51768138 | HCC515 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.22 | 1.24 |
| 117499 | BRD-K51768138 | HEPG2 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.63 |
| 117543 | BRD-K51768138 | HT29 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117586 | BRD-K51768138 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.15 | 1.06 |
| 117625 | BRD-K51768138 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |