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CMap Candidate Details

Structure:
CMap ID: C03144
Pert ID: BRD-K05236810
Compound Name: luteolin
Targets: TOP1
MoA: glucosidase inhibitor
SMILES: Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52056 BRD-K05236810 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.78
122623 BRD-K05236810 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122704 BRD-K05236810 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
122785 BRD-K05236810 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122808 BRD-K05236810 YAPC 0.37 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.42
130860 BRD-K05236810 A375 2.22 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
130880 BRD-K05236810 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130904 BRD-K05236810 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.49
130955 BRD-K05236810 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
130991 BRD-K05236810 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
131026 BRD-K05236810 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131109 BRD-K05236810 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).