CMap Candidate Details
Structure:
| CMap ID: | C03178 |
| Pert ID: | BRD-K17203476 |
| Compound Name: | LY2874455 |
| Targets: | FGFR1|FGFR2|FGFR3|FGFR4|KDR |
| MoA: | FGFR antagonist |
| SMILES: | C[C@@H](Oc1ccc2[nH]nc(\C=C\c3cnn(CCO)c3)c2c1)c1c(Cl)cncc1Cl |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120249 | BRD-K17203476 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.63 | 0.0 |
| 120288 | BRD-K17203476 | A549 | 3.33 uM | 24 h | -0.24 | -1.0 | 0.15 | 0.0 | 0.0 | 0.0 |
| 120348 | BRD-K17203476 | HELA | 1.11 uM | 24 h | 0.21 | 0.88 | 0.02 | 0.0 | 0.0 | 0.0 |
| 120412 | BRD-K17203476 | MCF??7.00 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120484 | BRD-K17203476 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128907 | BRD-K17203476 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.94 | 0.29 |
| 128952 | BRD-K17203476 | HT29 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128974 | BRD-K17203476 | PC3 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |