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CMap Candidate Details

Structure:
CMap ID: C03188
Pert ID: BRD-K78637815
Compound Name: LY320135
Targets: CNR1
MoA: cannabinoid receptor antagonist
SMILES: COc1ccc(cc1)-c1oc2cc(OC)ccc2c1C(=O)c1ccc(cc1)C#N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1627 BRD-K78637815 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
2127 BRD-K78637815 HCC515 10 uM 6 h 0.0 0.0 0.0 0.4 1.4 2.18
2423 BRD-K78637815 PC3 10 uM 6 h -0.27 -1.14 0.43 -0.31 -1.03 0.64
2625 BRD-K78637815 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41844 BRD-K78637815 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42146 BRD-K78637815 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42476 BRD-K78637815 ASC 10 uM 24 h -0.32 -1.33 0.9 0.0 0.0 0.0
42786 BRD-K78637815 HEPG2 10 uM 6 h -0.26 -1.08 0.29 -0.36 -1.22 1.25
43079 BRD-K78637815 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43357 BRD-K78637815 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.56
43651 BRD-K78637815 NPC 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.45 15.35
43953 BRD-K78637815 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44205 BRD-K78637815 SKB 10 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.46
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).