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CMap Candidate Details

Structure:
CMap ID: C03189
Pert ID: BRD-K95899059
Compound Name: LY344864
Targets: HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C|HTR7
MoA: serotonin receptor agonist
SMILES: CN(C)[C@@H]1CCc2[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc3c2C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6818 BRD-K95899059 A375 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.08
7199 BRD-K95899059 A549 10 uM 6 h 0.18 0.77 0.0 0.0 0.0 0.0
7366 BRD-K95899059 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
7734 BRD-K95899059 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8033 BRD-K95899059 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8192 BRD-K95899059 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8417 BRD-K95899059 PC3 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
8739 BRD-K95899059 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).