CMap Candidate Details
Structure:
| CMap ID: | C03223 |
| Pert ID: | BRD-A87130939 |
| Compound Name: | masoprocol |
| Targets: | ALOX5 |
| MoA: | lipoxygenase inhibitor |
| SMILES: | CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95306 | BRD-A87130939 | A549 | 10 uM | 24 h | 0.24 | 1.01 | 0.12 | 0.0 | 0.0 | 0.0 |
| 95351 | BRD-A87130939 | MCF??7.00 | 10 uM | 24 h | -0.17 | -0.72 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95464 | BRD-A87130939 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.91 | 0.24 |
| 125575 | BRD-A87130939 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125627 | BRD-A87130939 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125646 | BRD-A87130939 | HEK293 | 10 uM | 24 h | -0.29 | -1.21 | 0.58 | 0.0 | 0.0 | 0.0 |
| 125724 | BRD-A87130939 | HUVEC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125771 | BRD-A87130939 | JURKAT | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125798 | BRD-A87130939 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125870 | BRD-A87130939 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125923 | BRD-A87130939 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133759 | BRD-A87130939 | HELA | 2.22 uM | 24 h | -0.2 | -0.83 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133792 | BRD-A87130939 | HT29 | 2.22 uM | 24 h | -0.29 | -1.2 | 0.55 | 0.24 | 0.85 | 0.14 |
| 133907 | BRD-A87130939 | MDAMB231 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.2 |
| 133972 | BRD-A87130939 | THP1 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |