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CMap Candidate Details

Structure:
CMap ID: C03242
Pert ID: BRD-A50764878
Compound Name: MDL-73005EF
Targets: HTR1A
MoA: serotonin receptor antagonist
SMILES: O=C1CC2(CCCC2)CC(=O)N1CCNCC1COc2ccccc2O1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7552 BRD-A50764878 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.23
25477 BRD-A50764878 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.76
124712 BRD-A50764878 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
124773 BRD-A50764878 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124821 BRD-A50764878 PC3 0.37 uM 24 h 0.28 1.17 0.37 0.23 0.81 0.09
124864 BRD-A50764878 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132653 BRD-A50764878 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132676 BRD-A50764878 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132709 BRD-A50764878 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132734 BRD-A50764878 HEK293 0.03 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
132777 BRD-A50764878 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.62
132802 BRD-A50764878 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132851 BRD-A50764878 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132891 BRD-A50764878 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132938 BRD-A50764878 YAPC 0.01 uM 24 h 0.28 1.15 0.33 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).