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CMap Candidate Details

Structure:
CMap ID: C03264
Pert ID: BRD-K99615199
Compound Name: medroxyprogesterone
Targets: ESR1|PGR
MoA: progesterone receptor agonist
SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21859 BRD-K99615199 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22362 BRD-K99615199 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22617 BRD-K99615199 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22898 BRD-K99615199 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23206 BRD-K99615199 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.23 1.28
23491 BRD-K99615199 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23777 BRD-K99615199 MCF??7.00 10 uM 6 h -0.19 -0.78 0.0 0.22 0.78 0.07
23927 BRD-K99615199 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24365 BRD-K99615199 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96068 BRD-K99615199 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).