CMap Candidate Details
Structure:
| CMap ID: | C03267 |
| Pert ID: | BRD-K92778217 |
| Compound Name: | mefenamic-acid |
| Targets: | KCNQ1|PTGS1|PTGS2|TRPM3 |
| MoA: | cyclooxygenase inhibitor |
| SMILES: | Cc1cccc(Nc2ccccc2C(O)=O)c1C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1412 | BRD-K92778217 | A375 | 0.125 uM | 6 h | -0.2 | -0.85 | 0.01 | -0.27 | -0.92 | 0.33 |
| 1414 | BRD-K92778217 | HEK293T | 0.125 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3070 | BRD-K92778217 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3289 | BRD-K92778217 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3652 | BRD-K92778217 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3895 | BRD-K92778217 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44630 | BRD-K92778217 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.93 | 0.27 |
| 45052 | BRD-K92778217 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45338 | BRD-K92778217 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45597 | BRD-K92778217 | HT29 | 10 uM | 6 h | 0.24 | 0.99 | 0.1 | 0.0 | 0.0 | 0.0 |
| 45859 | BRD-K92778217 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.13 |
| 46161 | BRD-K92778217 | NPC | 10 uM | 24 h | -0.24 | -1.0 | 0.14 | 0.0 | 0.0 | 0.0 |
| 46476 | BRD-K92778217 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.88 |
| 46805 | BRD-K92778217 | SKB | 10 uM | 24 h | 0.3 | 1.24 | 0.53 | 0.37 | 1.3 | 1.55 |
| 91216 | BRD-K92778217 | HUH7 | 15 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |