CMap Candidate Details
Structure:
| CMap ID: | C03270 |
| Pert ID: | BRD-K19507340 |
| Compound Name: | megestrol-acetate |
| Targets: | NR3C1|PGR |
| MoA: | progesterone receptor agonist |
| SMILES: | CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6729 | BRD-K19507340 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7300 | BRD-K19507340 | HA1E | 10 uM | 24 h | -0.18 | -0.76 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7633 | BRD-K19507340 | HCC515 | 10 uM | 6 h | -0.26 | -1.07 | 0.26 | -0.29 | -0.98 | 0.49 |
| 7843 | BRD-K19507340 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.99 | 0.41 |
| 8231 | BRD-K19507340 | MCF??7.00 | 10 uM | 6 h | 0.29 | 1.21 | 0.45 | -0.28 | -0.95 | 0.41 |
| 8353 | BRD-K19507340 | PC3 | 10 uM | 24 h | 0.24 | 1.02 | 0.12 | -0.37 | -1.24 | 1.35 |
| 8652 | BRD-K19507340 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.33 |
| 24562 | BRD-K19507340 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 53012 | BRD-K19507340 | HEPG2 | 30 uM | 48 h | -0.2 | -0.85 | 0.01 | 0.0 | 0.0 | 0.0 |
| 53071 | BRD-K19507340 | MCF10A | 12 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |