CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03286
Pert ID:	BRD-A79803969
Compound Name:	memantine
Targets:	CHRFAM7A\|DRD2\|GRIN1\|GRIN2A\|GRIN2B\|GRIN3A\|HTR3A
MoA:	glutamate receptor antagonist
SMILES:	CC12CC3CC(C)(C1)CC(N)(C3)C2
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
49780	BRD-A79803969	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
49960	BRD-A79803969	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
50123	BRD-A79803969	HA1E	10 uM	6 h	0.0	0.0	0.0	-0.25	-0.85	0.19
50313	BRD-A79803969	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.41	-1.37	2.02
50474	BRD-A79803969	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
51110	BRD-A79803969	VCAP	10 uM	6 h	0.26	1.09	0.22	0.22	0.78	0.07
52107	BRD-A79803969	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
52253	BRD-A79803969	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary