Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03296
Pert ID: BRD-K18194590
Compound Name: mephentermine
Targets: ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|ADRB1|ADRB2|ADRB3
MoA: adrenergic receptor agonist
SMILES: CNC(C)(C)Cc1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5305 BRD-K18194590 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5760 BRD-K18194590 HCC515 10 uM 6 h 0.0 0.0 0.0 0.33 1.16 0.9
5892 BRD-K18194590 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6085 BRD-K18194590 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6526 BRD-K18194590 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37272 BRD-K18194590 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37607 BRD-K18194590 ASC 10 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
38438 BRD-K18194590 NPC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.08
38695 BRD-K18194590 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38920 BRD-K18194590 SKB 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
100171 BRD-K18194590 U2OS 10 uM 6 h -0.22 -0.93 0.07 0.26 0.91 0.23
120366 BRD-K18194590 HELA 0.125 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120388 BRD-K18194590 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120500 BRD-K18194590 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128898 BRD-K18194590 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128980 BRD-K18194590 PC3 0.03 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).