CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03331
Pert ID:	BRD-K56699285
Compound Name:	metergoline
Targets:	HTR1A\|HTR1B\|HTR1D\|HTR1E\|HTR1F\|HTR2A\|HTR2B\|HTR2C\|HTR5A\|HTR6\|HTR7
MoA:	dopamine receptor agonist; serotonin receptor antagonist
SMILES:	CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1cn(C)c3cccc2c13
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1589	BRD-K56699285	HA1E	10 uM	24 h	0.23	0.96	0.07	0.33	1.18	0.97
1926	BRD-K56699285	HCC515	10 uM	24 h	0.26	1.07	0.2	0.31	1.09	0.67
2486	BRD-K56699285	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41794	BRD-K56699285	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
41953	BRD-K56699285	A549	10 uM	24 h	0.21	0.88	0.01	0.0	0.0	0.0
42400	BRD-K56699285	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42719	BRD-K56699285	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43019	BRD-K56699285	HT29	10 uM	6 h	0.0	0.0	0.0	0.28	1.0	0.42
43584	BRD-K56699285	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43888	BRD-K56699285	PHH	10 uM	24 h	0.0	0.0	0.0	-0.37	-1.23	1.28
44144	BRD-K56699285	SKB	10 uM	24 h	0.0	0.0	0.0	0.35	1.23	1.24
51229	BRD-K56699285	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.02	0.59
51486	BRD-K56699285	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary