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CMap Candidate Details

Structure:
CMap ID: C03332
Pert ID: BRD-K79602928
Compound Name: metformin
Targets: ACACB|PRKAB1
MoA: insulin sensitizer
SMILES: CN(C)C(=N)NC(N)=N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50414 BRD-K79602928 HCC515 10 uM 6 h 0.0 0.0 0.0 0.25 0.89 0.21
51069 BRD-K79602928 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90968 BRD-K79602928 HUH7 25 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96282 BRD-K79602928 U2OS 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99092 BRD-K79602928 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99181 BRD-K79602928 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
119661 BRD-K79602928 HEPG2 10 uM 24 h 0.22 0.93 0.05 -0.25 -0.86 0.21
119698 BRD-K79602928 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119787 BRD-K79602928 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
127037 BRD-K79602928 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127059 BRD-K79602928 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127083 BRD-K79602928 HEK293 1.11 uM 24 h -0.27 -1.12 0.38 0.0 0.0 0.0
127194 BRD-K79602928 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127261 BRD-K79602928 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.28
127301 BRD-K79602928 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
127333 BRD-K79602928 YAPC 0.125 uM 24 h -0.22 -0.93 0.07 -0.28 -0.93 0.34
135068 BRD-K79602928 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135137 BRD-K79602928 HELA 2.22 uM 24 h -0.2 -0.85 0.01 0.23 0.82 0.1
135194 BRD-K79602928 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135294 BRD-K79602928 MDAMB231 0.03 uM 24 h 0.34 1.43 1.11 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).