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CMap Candidate Details

Structure:
CMap ID: C03339
Pert ID: BRD-K13356952
Compound Name: methazolamide
Targets: CA1|CA12|CA14|CA2|CA4|CA7
MoA: carbonic anhydrase inhibitor
SMILES: CC(=O)N=c1sc(nn1C)S(N)(=O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
51013 BRD-K13356952 VCAP 10 uM 24 h 0.23 0.95 0.07 -0.37 -1.26 1.35
52130 BRD-K13356952 MCF??7.00 10 uM 6 h -0.17 -0.71 0.0 0.0 0.0 0.0
122249 BRD-K13356952 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122359 BRD-K13356952 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122438 BRD-K13356952 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.02
122472 BRD-K13356952 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130553 BRD-K13356952 A549 0.25 uM 24 h -0.26 -1.08 0.29 -0.31 -1.04 0.67
130587 BRD-K13356952 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130623 BRD-K13356952 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130664 BRD-K13356952 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130704 BRD-K13356952 HT29 0.08 uM 24 h -0.18 -0.77 0.0 0.0 0.0 0.0
130781 BRD-K13356952 MDAMB231 0.01 uM 24 h -0.22 -0.91 0.05 -0.37 -1.25 1.35
130834 BRD-K13356952 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).