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CMap Candidate Details

Structure:
CMap ID: C03379
Pert ID: BRD-A33711280
Compound Name: metixene
Targets: CHRM1|CHRM2|CHRM3|CHRM4|CHRM5
MoA: acetylcholine receptor antagonist
SMILES: CN1CCCC(CC2c3ccccc3Sc3ccccc23)C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6633 BRD-A33711280 A375 10 uM 24 h -0.26 -1.08 0.29 0.28 0.99 0.39
7525 BRD-A33711280 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8566 BRD-A33711280 VCAP 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.71
120560 BRD-A33711280 A549 10 uM 24 h 0.0 0.0 0.0 0.42 1.5 2.27
120599 BRD-A33711280 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120623 BRD-A33711280 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120662 BRD-A33711280 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120714 BRD-A33711280 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120756 BRD-A33711280 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120781 BRD-A33711280 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120823 BRD-A33711280 YAPC 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).