CMap Candidate Details
Structure:
| CMap ID: | C03389 |
| Pert ID: | BRD-K46862739 |
| Compound Name: | metyrapone |
| Targets: | CYP11B1 |
| MoA: | cytochrome P450 inhibitor |
| SMILES: | CC(C)(C(=O)c1cccnc1)c1cccnc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6758 | BRD-K46862739 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7159 | BRD-K46862739 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7327 | BRD-K46862739 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7664 | BRD-K46862739 | HCC515 | 10 uM | 6 h | -0.21 | -0.88 | 0.03 | 0.0 | 0.0 | 0.0 |
| 8002 | BRD-K46862739 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8128 | BRD-K46862739 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8683 | BRD-K46862739 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.69 | 0.02 |
| 52299 | BRD-K46862739 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.78 | 0.09 |
| 99572 | BRD-K46862739 | U2OS | 8 uM | 6 h | -0.21 | -0.86 | 0.02 | -0.26 | -0.88 | 0.26 |