Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03405
Pert ID: BRD-A82396632
Compound Name: miconazole
Targets: KCNH2|KCNH6|KCNH7|KCNMA1|KCNMB1|KCNMB2|KCNMB3|KCNMB4|KCNN1|KCNN2|KCNN3|KCNN4|NOS2|NOS3|TRPM2|TRPV5
MoA: bacterial cell wall synthesis inhibitor
SMILES: Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91230 BRD-A82396632 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
100350 BRD-A82396632 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
125962 BRD-A82396632 A375 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.47 15.35
125981 BRD-A82396632 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126001 BRD-A82396632 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126049 BRD-A82396632 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126077 BRD-A82396632 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126122 BRD-A82396632 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126175 BRD-A82396632 MCF10A 10 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
126217 BRD-A82396632 MCF??7.00 10 uM 24 h 0.28 1.15 0.33 0.0 0.0 0.0
126260 BRD-A82396632 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126294 BRD-A82396632 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134096 BRD-A82396632 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
134144 BRD-A82396632 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134254 BRD-A82396632 MDAMB231 2.22 uM 24 h -0.22 -0.9 0.04 -0.25 -0.83 0.16
134309 BRD-A82396632 YAPC 0.01 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).