CMap Candidate Details
Structure:
| CMap ID: | C03412 |
| Pert ID: | BRD-A72066420 |
| Compound Name: | mifobate |
| Targets: | PPARG |
| MoA: | PPAR receptor antagonist |
| SMILES: | COP(=O)(OC)OC(c1ccc(Cl)cc1)P(=O)(OC)OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6686 | BRD-A72066420 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7109 | BRD-A72066420 | A549 | 10 uM | 6 h | 0.24 | 1.0 | 0.11 | 0.0 | 0.0 | 0.0 |
| 7968 | BRD-A72066420 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8777 | BRD-A72066420 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 100309 | BRD-A72066420 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.13 | 0.84 |
| 126678 | BRD-A72066420 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126727 | BRD-A72066420 | HELA | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126814 | BRD-A72066420 | MCF10A | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126857 | BRD-A72066420 | MCF??7.00 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126901 | BRD-A72066420 | MDAMB231 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 126970 | BRD-A72066420 | THP1 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 134778 | BRD-A72066420 | HEK293 | 0.03 uM | 24 h | -0.19 | -0.79 | 0.0 | 0.0 | 0.0 | 0.0 |
| 134884 | BRD-A72066420 | HUVEC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 134909 | BRD-A72066420 | JURKAT | 0.08 uM | 24 h | -0.22 | -0.9 | 0.04 | -0.26 | -0.86 | 0.21 |
| 134973 | BRD-A72066420 | PC3 | 0.08 uM | 24 h | 0.22 | 0.9 | 0.03 | -0.31 | -1.03 | 0.63 |
| 135001 | BRD-A72066420 | YAPC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.9 | 0.29 |