CMap Candidate Details
Structure:
| CMap ID: | C03416 |
| Pert ID: | BRD-A15202882 |
| Compound Name: | milnacipran |
| Targets: | GRIN1|GRIN2A|GRIN2B|GRIN2C|GRIN2D|GRIN3A|GRIN3B|SLC6A2|SLC6A4 |
| MoA: | serotonin norepinephrine reuptake inhibitor (SNRI) |
| SMILES: | CCN(CC)C(=O)C1(CC1CN)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122271 | BRD-A15202882 | A375 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122306 | BRD-A15202882 | HA1E | 10 uM | 24 h | 0.21 | 0.88 | 0.01 | -0.36 | -1.21 | 1.24 |
| 122324 | BRD-A15202882 | HEK293 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122375 | BRD-A15202882 | MCF10A | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.41 | -1.4 | 2.02 |
| 122402 | BRD-A15202882 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.86 | 0.22 |
| 122449 | BRD-A15202882 | PC3 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122496 | BRD-A15202882 | THP1 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122528 | BRD-A15202882 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.11 | 0.91 |
| 130571 | BRD-A15202882 | A549 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130683 | BRD-A15202882 | HELA | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.52 |
| 130726 | BRD-A15202882 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130798 | BRD-A15202882 | MDAMB231 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |