CMap Candidate Details
Structure:
| CMap ID: | C03418 |
| Pert ID: | BRD-A31811760 |
| Compound Name: | miltefosine |
| Targets: | PLA2G1B |
| MoA: | membrane integrity inhibitor |
| SMILES: | CCCCCCCCCCCCCCCCOP(O)(=O)OCC[N+](C)(C)C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91076 | BRD-A31811760 | HUH7 | 8 uM | 72 h | -0.19 | -0.79 | 0.0 | 0.27 | 0.95 | 0.32 |
| 120514 | BRD-A31811760 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120549 | BRD-A31811760 | A549 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120650 | BRD-A31811760 | HT29 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120700 | BRD-A31811760 | JURKAT | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120749 | BRD-A31811760 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120772 | BRD-A31811760 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.82 | 0.15 |
| 120806 | BRD-A31811760 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.91 | 0.3 |
| 129002 | BRD-A31811760 | HA1E | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.91 | 0.31 |
| 129031 | BRD-A31811760 | HELA | 0.03 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |