Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C00344
Pert ID: BRD-A53566267
Compound Name: anecortave-acetate
Targets:
MoA: angiogenesis inhibitor
SMILES: CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3=CC[C@]12C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124350 BRD-A53566267 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124382 BRD-A53566267 HT29 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.69
124415 BRD-A53566267 JURKAT 0.04 uM 24 h 0.2 0.85 0.0 -0.3 -1.0 0.53
124465 BRD-A53566267 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124516 BRD-A53566267 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132329 BRD-A53566267 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132356 BRD-A53566267 A549 0.08 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.47
132387 BRD-A53566267 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.22
132421 BRD-A53566267 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132492 BRD-A53566267 MCF10A 0.08 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
132551 BRD-A53566267 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132602 BRD-A53566267 THP1 0.25 uM 24 h 0.29 1.2 0.43 -0.38 -1.27 1.39
132641 BRD-A53566267 YAPC 0.01 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).