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CMap Candidate Details

Structure:
CMap ID: C03505
Pert ID: BRD-A16332958
Compound Name: modafinil
Targets: ADRA1B|SLC6A3
MoA: adrenergic receptor agonist
SMILES: NC(=O)CS(=O)C(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1455 BRD-A16332958 NPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4005 BRD-A16332958 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4277 BRD-A16332958 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25279 BRD-A16332958 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37045 BRD-A16332958 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37214 BRD-A16332958 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.1
37447 BRD-A16332958 ASC 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
37788 BRD-A16332958 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37985 BRD-A16332958 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38603 BRD-A16332958 PHH 10 uM 24 h -0.3 -1.25 0.7 0.0 0.0 0.0
51553 BRD-A16332958 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51774 BRD-A16332958 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).