CMap Candidate Details
Structure:
| CMap ID: | C03513 |
| Pert ID: | BRD-K63861289 |
| Compound Name: | molsidomine |
| Targets: | GUCY1A3 |
| MoA: | guanylate cyclase stimulant |
| SMILES: | CCOC(=O)Nc1c[n+](no1)N1CCOCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 99325 | BRD-K63861289 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124588 | BRD-K63861289 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124630 | BRD-K63861289 | HA1E | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124675 | BRD-K63861289 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124710 | BRD-K63861289 | HT29 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124749 | BRD-K63861289 | MCF10A | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124859 | BRD-K63861289 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124900 | BRD-K63861289 | THP1 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132706 | BRD-K63861289 | A549 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132773 | BRD-K63861289 | HEK293 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.99 | 0.39 |
| 132847 | BRD-K63861289 | JURKAT | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132912 | BRD-K63861289 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.19 | 1.03 |
| 132922 | BRD-K63861289 | MDAMB231 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132969 | BRD-K63861289 | YAPC | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.13 | 0.82 |