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CMap Candidate Details

Structure:
CMap ID: C03538
Pert ID: BRD-K77771411
Compound Name: moxonidine
Targets: ADRA2A|ADRA2B|ADRA2C
MoA: imidazoline receptor agonist
SMILES: COc1nc(C)nc(Cl)c1NC1=NCCN1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4596 BRD-K77771411 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24478 BRD-K77771411 A375 10 uM 6 h -0.2 -0.83 0.0 0.0 0.0 0.0
24608 BRD-K77771411 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25420 BRD-K77771411 VCAP 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
39764 BRD-K77771411 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40058 BRD-K77771411 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40866 BRD-K77771411 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41183 BRD-K77771411 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90618 BRD-K77771411 HCT116 10 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
90666 BRD-K77771411 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
97977 BRD-K77771411 HA1E 0.04 uM 24 h -0.2 -0.81 0.0 0.27 0.97 0.35
98048 BRD-K77771411 P1A82 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99499 BRD-K77771411 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121765 BRD-K77771411 HELA 0.125 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
121796 BRD-K77771411 HT29 3.33 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
129830 BRD-K77771411 HEK293 0.74 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
129918 BRD-K77771411 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130001 BRD-K77771411 MCF??7.00 0.08 uM 24 h -0.24 -0.99 0.13 -0.29 -0.98 0.48
130041 BRD-K77771411 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
130082 BRD-K77771411 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130113 BRD-K77771411 THP1 0.74 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
130159 BRD-K77771411 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).