CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03539
Pert ID:	BRD-A31095847
Compound Name:	mozavaptan
Targets:	AVPR1A\|AVPR1B\|AVPR2
MoA:	vasopressin receptor antagonist
SMILES:	CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
96611	BRD-A31095847	A375	3.33 uM	24 h	-0.25	-1.03	0.2	0.22	0.79	0.07
96683	BRD-A31095847	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121920	BRD-A31095847	A549	10 uM	24 h	0.3	1.23	0.5	-0.34	-1.16	1.11
121937	BRD-A31095847	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.37	-1.23	1.28
121964	BRD-A31095847	HEK293	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.68
121985	BRD-A31095847	HELA	10 uM	24 h	0.0	0.0	0.0	-0.39	-1.31	1.68
122013	BRD-A31095847	HT29	10 uM	24 h	0.0	0.0	0.0	0.24	0.87	0.17
122059	BRD-A31095847	HUVEC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122090	BRD-A31095847	MCF10A	10 uM	24 h	0.0	0.0	0.0	-0.43	-1.45	15.35
122113	BRD-A31095847	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.25	-0.83	0.17
122145	BRD-A31095847	MDAMB231	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.13	0.97
122198	BRD-A31095847	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122221	BRD-A31095847	YAPC	10 uM	24 h	-0.23	-0.96	0.1	0.0	0.0	0.0
130360	BRD-A31095847	JURKAT	0.08 uM	24 h	0.19	0.78	0.0	0.0	0.0	0.0

Summary